Well, first of all, if he is healthy (that is a big if, I know), Wade makes up a LOT of ground there.
But I also think it is pointless to break down a team like the Heat by position, because their best player is so much better than just about anyone else in the league, and is so versatile. When you add in Wade and Bosh, it allows them to have more "specialists" than any other team in the league.
I certainly hope the C's can beat the Heat, and I think its definitely possible, if they are healthy, and their chemistry clicks. But, there will be nothing easy about it.