Statistically Crawford has been at his best hitting 2nd, has an OPS of .812 there, compared to sub 800 when hitting leadoff or 3rd. But i don't really think that matters a ton now, different situation. I'd also hope that Lowrie is the starting SS over Scutaro, if healthy of course which is the big question with him. Francona also loves to split up his lefties and righties, so a lineup i'd like is
Crawford
Pedroia
A-Gon
Youkilis
Ortiz
Lowrie
Drew
Salty/whoever
Ellsbury/Cameron
Francona said last week Ellsbury was still feeling pain in his back, not a good sign. There's too many question marks with him to pencil him in at leadoff IMO. And if Lowrie gets hurt again, just move Drew to the 6 spot, and have Scutaro hit 7th or 8th.