It's Always Sunny is definitely my favorite, followed closely by The Office. Big Bang Theory, Letterkenny, and Arrested Development are up there, too. My Name is Earl and Raising Hope are two of my other favorites.
If counting animation, Archer (at least the first 6-7 seasons) and Rick and Morty have to be up there, as well as Bob's Burgers and Family Guy following behind. (By the way - anyone watched the Bob's Burgers movie?)