Did not know it's set in BOS
Will make for interesting gameplay, to say the least.
Makes sense, though - if I recall correctly, Dr. Lee from Fallout 3 (Scientist that was helping to engineer pure water for the inhabitants of The Wasteland), ventured towards BOSTON as her part in number 3 closed out....if I remember correctly, The Commonwealth (some organization that engineered robots or cyborgs) originates in BOS - I think.
Looking forward to whatever story branch happens. Loved the story as much as the gameplay from Fallout 3.
As long as THE STORY is as good as number 3, game will be fine.