Ok, looking at these stats I can see some small pros and cons, but there are a few
major issues that really stand out:
1. Kevin Garnett's backupWhen KG is on the court we are 5.57 points better off defensively (Def Rating: 97.73, 4th best in the league).
When KG is off the court we are 8.08 points worse off defensively (Def Rating: 111.31, last in the league).
Every single Celtics fan knows that our team turns to disaster when KG is on the bench. These figures tell us that 40% of this is because KG's defense is so good, and 60% of this is because our backup centers are so darn bad.
To put things into perspective the current worst defensive team in the league is the Bobcats, who have a defensive rating of 108.9. with KG on the bench we have a defensive rating of 111.31 - this is > 2 points worse than the worst defense in the NBA! Yikes!
I think this clearly identifies a need for another big man who's capable of defending the paint while KG sits. This won't be enough for us to build leads, but it should at least allow us to hold them!
Scoring behind Paul PierceStatistics show that we are almost as bad offensively when PP34 sits as we are defensively when KG sits.
When Pierce is on the court our offense is +3.28 compared to our team average, with out offensive rating of 105.6 being good for 7th in the league
When Pierce is off the court our offensive is a -7.98 compared to our team average. Our offensive rating (94.34) is good for second worst in the league, with only the Wizards offense (92.

being worse then ours is when the Captain sits.
Similar to the KG situation, the stats here indicate that ths is 30% due to Pierce's excellent offensive ability and 70% due to the poor offensive play of the guys who back Pierce up.
Sure enough Pierce's primary backups are Jeff Green and Courtney Lee who are are two of our worst offensive players with ratings of -6.08 and -3.80 respectively.
The numbers show that Lee is barely worse the Pierce defensively, while Green is actually significantly better defensively than Pierce. This shows that offense off our bench is clearly a problem - either Lee or Green needs to replaced by a pure scoring swingman who can consistently put points on the board.
3. Jason Terry's backupJason Terry and Jared Sullinger are the only players on our roster who benefit us (statistically) on both ends of the floor.
Terry is one of our better defensive players (-1.8 vs team average) and our defensive rating of 101.5 suggests that we are an average defensive team (15th in the league) when Terry is on the court.
The surprising result is that we are 3.08 poits worse off when Terry sits, with our defensive rating of 106.38 being good for 27th in the league when Terry is on the bench.
This suggests that Terry is doing a solid job defensively when he's on the court, but whoever replaces him when he sits down (typically Barbosa or Lee) has been horrendous on that end of the floor.
Sure enough Lee (+3.26) is the third worst defensive player on the team, while Barbosa (+7.34) is the worst.
This clearly identifies the need for another strong defensive backcourt player either to back up Terry or to start (and be backed up by Terry). With the imminent return of Avery Bradley, this shouldn't be a problem for long.
4. Backup for Rajon Rondo
Our second biggest ofensive hit happens when Rajon Rondo isn't playing.
We are a +1.72 on offense (104.04 Off Rating, Ranked top 10 in the league) when Rondo plays, but we are a -3.67 (98.65 Off Rtg, ranked 28th in the league) when he is on the bench.
This exposes another weakness for our our team, and that is the backup PG spot. When Rondo sits we need a backup PG who can give us a net positive (or at least neutral) impact on offense, whether it be via scoring or via playmaking.
Leandro Barbosa is clearly not doing that, as our offensive rating (94.25) with him on the court is just as bad as our offensive rating (94.34) with Paul Pierce off the court.
Trade optionsLooking at our current roster, it's clear that we'd like KG, Pierce, Terry, Rondo, Bradley and Sullinger to stay on board.
Chris Wilcox and Brandon Bass both help us on offense, but they both hurt us on defense. If we need to keep one then we are better off with Wilcox because he helps us more on offense (+4.5) than Bass (+2.7) and he doesn't hurt us as much on defense (-3.2 vs -6.34). Add to that the fact that Wilcox is on a wallet friendly minimum contract and clear Bass is the better of the two to trade.
Jeff Green is the second worst player on our team on offense (-6.08) but defensively his defensive rating (0.02) is actually 4th best on the team. I believe his offense will improve, so I don't mind keeping Green unless an "offer you cant refuse" type deal comes alone.
Collins, Lee and Barbosa are the clearly bad ones. All three of those guys are hurting us on both ends of the floor when they are on the court, and we are better when they are sitting on the bench. That's a perfect sign of a guy you need to let go.
So in summary I would be putting Bass, Collins, Lee and Barbosa (along with a 1st Rd pick) on the trading block in the hope of picking up a solid defensive big man to back up KG and either:
1. A backup PG for Rondo
or
2. A consistent volume scorer to lead the bench offensively