Not a chance.
KG is the starting C.
I could see Sullinger eventually taking over as starting PF over Bass, but not Melo. To much of a project.
Essentially this, plus more.
Even if we entertain the idea that Melo is a contributor this year, it just doesn't make much sense to start him.
First, KG has proven to be an elite center and a big mismach problem for other centers. We lose a lot of that if he goes back to facing more mobile power forwards.
Second, too much of this team's talent is focused at the PF spot. We have Bass, Sullinger, and Green who could all use minutes there. Putting KG there just eats into that time when he could be playing next to them, not instead of them.
I think if Melo proves that he's ready for action, he should be the backup center. That'd still get him about 20 minutes a game and frees up the PF minutes to allow Bass, Green, and Sullinger to get PT there.