I think the nominations in general seem pretty reasonable, but I'm a bit shocked that The Dark Knight didn't get a nomination for best picture. Even though I'm sure it would never win the award, it deserves the recognition, as I'm sure most would agree it's one of the best movies of 2008.
I also think it's a bit strange that Fincher got a nomination for The Curious Case of Benjamin Button, but didn't get any for Fight Club or Se7en. This isn't his best movie or direction so far, at least not in my oppinion..