If the plan is to play him as a starting SG, It could mess with their chemestry. You see, I think what makes the Cavs chemestry work so well is how DWest stabilizes their backcourt. You let MWilliams roam and do as he pleases or let LeBron be your point-fwd, you'll see that ball movement getting worse and worse and easier to defend.
LeBron is a stud, of that no doubt. But big Z and Dolante can't be replaced as starters. You mess with that, you are asking for trouble.