Always better to have the #1 pick. We're gunshy from teh Oden/Durant thing, but overall look at #1 vs #2 through history.
2013 was weird.
2012: Davis vs MKG
2011: Irving vs Williams
2010: Wall vs Turner
2009: Griffin vs Thabeet
2008: Rose vs Beasley
2007*: Oden vs Durant
2006*: Bargs vs Aldridge
2005: Bogut vs Williams (Bogut way better, but both screwed that draft up)
2004: Dwight vs Okafor
2003: James vs Darko
2002: Yao vs J Will
2001*: Kwame vs Tyson
2000: Kenyon vs Stromile
1999: Brand vs Francis
1998*: Kandi vs Bibby
1997: Duncan vs Van Horn
Now, you don't always get the best player with the #1 pick, but I wouldn't be praying for the 10th pick in a draft because that's where Pierce and George were taken. But overwhelmingly the #1 pick is much better than the #2. Just don't mess it up. Interestingly, the major mess ups above, 1 was injury related, and the other three were taking Bigs without "traditional" scouting data (High school, italian league, and a 22 year old Jr who had 2 bad years of evidence then suddenly put up great numbers at Pacific).