My first reply in a long time...
I am one of those audiophile types. People often drop their jaws in shock when they learn about my stereo systems, and I suppose rightfully so.
Fortunately, even though I am eccentric with my own purchases, I can also look at the whole thing realistically. I'll do my best to do that for you.
Most of what has been said here is true, but I want to point out a few key points:
-Bose is not the best sound quality for the money, or even close, at any price point. That being said, they offer attractive warranties that they seriously back up, and their products have nice features for the size unit.
-Used is always the best value; I do my best to buy used always. Out of my 3 systems, my best features a rare set of Yamaha NS-1000X speakers from *1980*,complete with carbon fiber woofers and beryllium midranges and tweeters. The technology has not changed enough (in speakers at least) to negate the discount in buying used. Ebay is your friend.
-The Edirol speakers that were recommended are active, meaning that not only is the amplifier built in, but there is an amplifier for each 'driver' in the speaker. This is highly beneficial for many many reasons, to the point where I was able to even give a whole lecture once on the benefits of active speakers. My secondary system features active speakers (Fostex NF-1A's). I would greatly recommend getting active speakers, and those Edirol's are a fantastic recommendation if that is the price point you are looking at...next point...
-Pick a price point. Good sound can be had for almost any price if properly chosen. It goes without saying that the more you spend the better, but you would be impressed how far even $100 can take you if spent wisely.
-Go with what appeals to you, sound and features. For years I was laughed at in the audiophile community for having a computer based system (I built my first htpc in...*1999*), now it is common place. There is a lot of bs out there in the audio world, so stick with what you want.
-The pro market can be a great starting point. There is very little marketing and hype there, performance always matters most, and margins are very small.
-Please feel free to PM me with products you are considering and I will give you feedback individually on them.
Here is a link of professional active speakers, I recommend taking a look at them and see if any questions arise:
http://www.zzounds.com/prodsearch?cat=2864&cat2=&rl=&rh=&instock=0&blowouts=0&ob=p19&filter=&q=&form=search