No one is going to take Dwight Howard single handedly.

Seriously now, Big Baby shall be able to play him at least some minutes. If we need a 3rd player, I'd go with Moore - he must try to front him; once unsuccessful, proceed to foul him.
I can't remember Moore's coaches trusting him to stop perimeter oriented players, he's too prone to foul jump-shooters and close out without self control; they generally prefer to deal with his weaknesses as a post defender.