I don't think they're gonna beat LA, but it is a really good situation for an upset. LA is reeling a bit - Kobe's playing inefficiently lately, Fisher looks old, and Artest isn't doing much on offense. Bynum is also coming back and will probably be a net negative for at least the first couple of games.
OKC has clear advantages at PG and SF, and one of the best Kobe-stoppers in the league in Sefolosha. And the place where they're weakest - the front court - is where the Lakers normally dominate but again are gonna have to spend minutes getting Bynum acclimated.
I think we'll see a very tight series, but one where LA takes advantage of OKC's inexperience and steadily pulls away. I predict OKC goes up 2-1 but the Lakers win in 6.