In short, no. They've lost their best defender and their best fastbreak weapon. He also gives them the potential for unique lineups that are hard to defend. Now they're a lot more predictable.
Beating Houston was nothing. Harden didn't play 30 minutes, and Caboclo, Clemens and Michael Frazier (who?) all played 17 minutes. Even Luc Mbah a Moute played 14 minutes, which is more minutes than he'd played in the bubble in total. Nothing to see.
Oh, and Russ is hurt.